I've been running these for a long time now and they've been fine. Not revolutionary or anything, but I'm happy with them. It weighs more for 4 gallons of water than four gallons of gas more so because you have more bul/material for two separate cans instead on one flow-through fuel can. They do vent up and bulge more than my NATO cans, so you might want to be wary of running them less than full; keeps the amount of vapor down as opposed to liquid.
I only moved the spare tire out the thickness of the can. On one side it slides up and out and the other I can pull out sideways. Nothing impedes access to anything else nor does any one thing have to be moved to access another.
As for departure angle, my spare is so high off the ground that it really hasn't mattered and it will matter even less with the 35s.
I have modified the water cans, though. I drilled the sides top and bottom to add a drain and vent. After adding a screw on hose fitting, they now have an easy on/off place to draw water, wash hands, head, etc.
FYI if you want to pick up a spare spout/gasket, skip the $10+ ones sold at the sites. Go to Pep Boys or the like and just get one over by the water jugs -- it's the same sceptor spout but they sell it for $4.99.
